The Peru Guide

How to get to Iquitos and the Amazon from Lima or Cusco

You fly. Iquitos is the largest city in the world with no road connection, and the southern gateway, Puerto Maldonado, is a short flight from Cusco. Here is how the connections work for each side of the Peruvian Amazon and how we build them into a trip.

Lima to Iquitos

Direct flights from Lima’s Jorge Chávez airport to Iquitos take about two hours and run daily. There is no road and no practical river route for travelers, so the flight is the only way in. Morning departures are the most reliable for connecting to a same-day embarkation.

If you land in Lima on an overnight international flight, we usually recommend one night in Miraflores before flying north. It removes the risk of a missed connection and starts the Amazon rested.

From Iquitos to the ship

Aqua Expeditions embarks at Nauta, south of Iquitos by road, where the Marañón and Ucayali meet to form the Amazon. Aqua Expeditions meets you for the transfer to the ship, and the return works in reverse, timed to your flight out.

Cusco to Puerto Maldonado

The southern Amazon is simpler to reach from the Andes. Flights from Cusco to Puerto Maldonado take under an hour, and Inkaterra Reserva Amazónica meets you at the airport for the short drive and boat ride up the Madre de Dios River. This is the connection we use on Exploration of Peru.

Connecting the Amazon and the Andes

There is no direct flight between Iquitos and Cusco; you travel via Lima, a full travel day. We plan that day with a buffer at each end and a private transfer waiting in Cusco, and we start you in the Sacred Valley rather than the city so you arrive at a lower altitude after a long day.

Doing the Amazon first, at sea level, and the Andes second is the order we prefer. You acclimatize later in the trip, with the river already behind you.

What we book for you

Flights are not included in our published prices, but we book them for you for a small fee and manage the connections, so one change does not unravel the rest. Our Amazon & Andes journey shows the whole sequence from Lima to Cusco.

A few useful answers

Before you go.

Can I take a boat to Iquitos instead?

Cargo boats run the river from Yurimaguas and Pucallpa, but they take days and are not something we offer. Fly.

How early should I arrive in Iquitos for the sailing?

A morning flight from Lima on the sailing day usually works; an earlier arrival is safer if your international flight lands late the night before. Departures run several times a week, and we match the sailing to your dates.

Is there a yellow fever requirement for the flight?

No certificate is required for domestic flights or entry to Peru, but vaccination is recommended for the Amazon lowlands. Check with a travel clinic.

Your Peru, privately designed

Begin your journey.

Send us your dates and where you’d like to start. We’ll plan the flights and the order so the Amazon and the Andes connect without a wasted day.

Plan your journey